大理大学学报 ›› 2021, Vol. 6 ›› Issue (8): 50-53.DOI: 10. 3969 / j. issn. 2096-2266. 2021. 08. 011

• 基础医学 • 上一篇    下一篇

美洲大蠊提取物对精神疾病患者肠道菌群影响的研究

尹春蕾1,王 楠1,马莹莹1,贾乘一1,张 倩1,李丽娟2*   

  1. (1. 大理大学公共卫生学院,云南大理 671000;2. 大理大学澜湄人类健康研究中心,
    云南大理 671000)
  • 收稿日期:2020-04-17 修回日期:2020-09-15 出版日期:2021-08-15 发布日期:2021-09-28
  • 通讯作者: 李丽娟,教授,E-mail:lelejuan@126.com。
  • 作者简介:尹春蕾,硕士研究生,主要从事流行病与卫生统计学研究。
  • 基金资助:
    云南省地方本科高校(部分)基础研究联合专项资金项目(202001BA070001-065)

Effect of Periplaneta americana Extract on Intestinal Flora in Patients with Mental Illness

Yin Chunlei1, Wang Nan1, Ma Yingying1, Jia Chengyi1, Zhang Qian1, Li Lijuan2*#br#   

  1. (1. College of Public Health, Dali University, Dali, Yunnan 671000, China; 2. Lan Mae Human Health Research Center of Dali
    University, Dali, Yunnan, 671000, China)
  • Received:2020-04-17 Revised:2020-09-15 Online:2021-08-15 Published:2021-09-28

摘要: 目的:探究美洲大蠊提取物对精神疾病患者肠道菌群是否有影响。方法:采集19 例精神疾病患者发作期和控制期的粪
便样本,对其进行微生物共培养,对菌落数进行统计学分析。结果:3 类微生物(需养菌、厌氧菌、真菌)的3 种样本(空白组、
实验组、阳性组)菌落数两两比较,空白组与实验组、空白组与阳性组(除女性和精神分裂特征的需氧菌组)的菌落数差异均
有统计学意义(P<0.05)。结论:美洲大蠊提取物对精神疾病患者的肠道菌群有调节作用。

关键词: 美洲大蠊提取物, 精神疾病, 肠道菌群, 微生物共培养

Abstract: Objective: To investigate whether the extract of Periplaneta americana has an effect on the intestinal flora of patients
with mental illness. Methods: Fecal samples collected from 19 patients with mental illness during the onset and control periods were
co-cultured with microorganisms, and the number of colonies was analyzed statistically. Results: The number of colonies in each of
the three samples (blank group, experimental group, and positive group) of the three types of microorganisms (aerobic bacteria,
anaerobic bacteria, fungi) was compared in pairs. The differences in the number of colonies between the blank group and the
experimental group, the blank group and the positive group ( aerobic bacteria group except female and schizophrenic characteristics )
were statistically significant (P<0.05). Conclusion: The extract of Periplaneta americana can regulate the intestinal flora of patients
with mental illness.

Key words: Periplaneta americana extract, mental illness, intestinal flora, microbial co-culture

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